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Biostimulators

Injectable biostimulators are advanced aesthetic treatments designed to stimulate collagen production naturally, improving skin quality over time.

Unlike traditional fillers, which add volume instantly, collagen stimulators work gradually to:

  • Improve skin elasticity
  • Restore firmness
  • Reduce fine lines and wrinkles
  • Strengthen the skin’s structure

These treatments are ideal for patients seeking natural-looking facial rejuvenation without overfilling.

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Contents

Overview

  • PROCEDURE: Injectable collagen biostimulation (Juläine®)
  • KEY COMPONENT: Poly-L-lactic acid (PLLA), a biocompatible material that the body breaks down gradually
  • TREATMENT AREAS: Face
  • SESSIONS: Tailored to you and agreed at consultation
  • RESULTS: Develop gradually over weeks to months; reported to last up to two years
  • DOWNTIME: Mild swelling, redness or bruising for a few days
Overview

Juläine

Juläine® is an injectable treatment designed to improve skin quality when injected into the deeper layers of the skin, where it encourages your body to produce more collagen.

Collagen is a natural protein that keeps the skin firm, smooth, and youthful. As we age, collagen levels decline, leading to:

  • Fine lines and wrinkles
  • Loss of firmness
  • Thinning skin

Juläine® helps to reverse these changes by stimulating natural regeneration, resulting in healthier, stronger skin over time

It is made from a biocompatible substance called poly-L-Lactic acid (PLLA) that is naturally broken down by the body over time.

As with any injectable treatment, there are small risks, which will be discussed during your consultation.

Juläine

What the procedure involves

  1. Consultation: Your skin and facial structure are assessed, with an honest discussion of what biostimulation can and cannot achieve for you.
  2. Preparation: The skin is cleansed and anaesthetic is used for comfort.
  3. Treatment: The product is injected into the deeper layers of the skin in the planned areas.
  4. Afterwards: You can usually return to normal activities the same day. Results develop gradually as new collagen forms.

Benefits and expected outcomes

  • Gradual, natural-looking change: Improvement develops as your own collagen forms, avoiding an overfilled appearance.
  • Firmer skin: Better elasticity and structural support over time.
  • Long-lasting results: Improvement has been reported to last up to two years, although this varies between patients.

Ideal candidates

  • Adults with age-related loss of skin firmness: Particularly those who prefer gradual change to an immediate one.
  • Those not seeking instant volume: Biostimulators are not a substitute for dermal filler where immediate volume is the aim.
  • Not suitable: During pregnancy or breastfeeding, or with an active skin infection at the treatment site.

Risks and considerations

  • Common and temporary: Swelling, redness, bruising and tenderness at the injection sites, settling over a few days.
  • Uncommon: Small firm areas or nodules under the skin. These usually settle on their own but can occasionally persist and need treatment.
  • Rare: Infection or allergic reaction.

All risks are discussed with you at consultation before any treatment.

Aftercare and recovery

Mild swelling, redness or bruising is normal and settles over a few days. Avoid make-up for 24 hours and strenuous exercise for 48 hours.

You will be given specific aftercare instructions at your appointment, and you can contact the hospital at any point if you have concerns.

aftercare

Frequently asked questions about biostimulators

What is a biostimulator?
An injectable treatment that stimulates your own collagen production, gradually improving skin firmness and quality. It works differently from a filler, which adds volume directly.
What is Juläine?
Juläine® is a poly-L-lactic acid (PLLA) biostimulator developed by Nordberg Medical in Sweden. The PLLA is biocompatible and broken down naturally by the body over time.
When will I see results?
Improvement is gradual, developing over weeks to months as new collagen forms. This is normal and is how the treatment is designed to work.
How long do results last?
Results have been reported to last up to two years, although this varies between patients.
How many sessions will I need?
This depends on your skin and what you want to achieve. Your practitioner will agree a plan with you at consultation.
Is it safe?
PLLA has been used in medicine for many years and is broken down naturally by the body. As with any injectable treatment there are risks, and these are discussed at your consultation.

Author

Waterfront non surgical pricing Katy Nassar

Dr. Katy Nassar, BDS, GDC 80528, is an Aesthetic Practitioner at Waterfront Private Hospital in Edinburgh. She graduated from the University of Glasgow Dental School in 2002 and worked in general dental practice for fifteen years before moving into facial aesthetics. In 2022, she completed a Master’s degree in Skin Ageing & Aesthetic Medicine at Manchester University, which she was awarded with distinction. Katy is dedicated to expanding the range of non-surgical procedures offered at Waterfront Private Hospital.

Waterfront Private Hospital Edinburgh

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